abstract：:Socially housed mice with cytotoxic lesions of the hippocampus do not exhibit social recognition memory 30 min following exposure to a juvenile mouse, however the social recognition memory of singly housed rats is unimpaired. The present study tests the hypothesis that social housing of rats could render social recogn...

journal_title：Neurobiology of learning and memory

authors： Squires AS,Peddle R,Milway SJ,Harley CW

更新日期：2006-01-01 00:00:00

abstract：:In the wild, house mice live in social groups, whereas in the laboratory male mice are often singly housed. Environmental enrichment such as that provided by social housing has been argued to improve the cognitive performance of laboratory animals in experimental tests. The aim of the present study was to test the cos...

journal_title：Neurobiology of learning and memory

authors： Fitchett AE,Collins SA,Barnard CJ,Cassaday HJ

更新日期：2005-11-01 00:00:00

abstract：:Human episodic memory refers to the recollection of an unique past experience in terms of what happened, and where and when it happened. Factoring out the issue of conscious recollection, episodic memory, even at the behavioral level, has been difficult to demonstrate in non-human mammals. Although, it was previously ...

journal_title：Neurobiology of learning and memory

authors： Dere E,Huston JP,De Souza Silva MA

更新日期：2005-11-01 00:00:00

abstract：:This study was undertaken to verify the effects of chronic stress and lithium treatments on the hippocampal Na+,K(+)-ATPase activity of rats, as well as to investigate the effects of stress interruption and post-stress lithium treatment on this enzyme activity and on spatial memory. Two experiments were carried out; i...

journal_title：Neurobiology of learning and memory

authors： de Vasconcellos AP,Zugno AI,Dos Santos AH,Nietto FB,Crema LM,Gonçalves M,Franzon R,de Souza Wyse AT,da Rocha ER,Dalmaz C

更新日期：2005-09-01 00:00:00

abstract：:Conditioning-specific reflex modification (CRM) of the rabbit's nictitating membrane response (NMR) involves changes in responding to an unconditioned stimulus (US) when the US is tested in the absence of the conditioned stimulus. Previous experiments have shown that CRM is a function of the type and intensity of the ...

journal_title：Neurobiology of learning and memory

authors： Schreurs BG,Smith-Bell CA

更新日期：2005-09-01 00:00:00

abstract：:Both the acquisition and the extinction of memories leave short- and long-term mnemonic traces. Here, we show that in male Wistar rats, the short-term memory for a step-down inhibitory avoidance task (IA) is resistant to extinction, and that its expression does not influence retrieval or extinction of long-term memory...

journal_title：Neurobiology of learning and memory

authors： Cammarota M,Bevilaqua LR,Rossato JI,Ramirez M,Medina JH,Izquierdo I

更新日期：2005-07-01 00:00:00

abstract：:It has been well established that moderate physiological or emotional arousal modulates memory. However, there is some controversy about whether the source of arousal must be semantically related to the information to be remembered. To test this idea, 35 healthy young adult participants learned a list of common nouns ...

journal_title：Neurobiology of learning and memory

authors： Nielson KA,Yee D,Erickson KI

更新日期：2005-07-01 00:00:00

abstract：:Carbon monoxide (CO) is most often thought of as an exogenous toxin rather than as a possible endogenous nootrope. However, a limited number of studies have suggested that CO is necessary in memory processing for at least some tasks. While nitric oxide (NO) and CO are known activators of guanylyl cyclase (GC), only th...

journal_title：Neurobiology of learning and memory

authors： Cutajar MC,Edwards TM,Ng KT

更新日期：2005-05-01 00:00:00

abstract：:Studies in rodents have demonstrated that glucocorticoids enhance memory consolidation but impair delayed memory retrieval. Similar findings have been reported in humans. Emotional items are better remembered than neutral items. However, it is unknown if emotional valence influences the effects of cortisol on retrieva...

journal_title：Neurobiology of learning and memory

authors： Kuhlmann S,Kirschbaum C,Wolf OT

更新日期：2005-03-01 00:00:00

abstract：:Based on computational models of the hippocampus, it has been suggested that a possible mechanism for memory retrieval is pattern completion, wherein an autoassociative network recalls previous patterns of activity given noisy or degraded cues. However, there are few behavioral data examining pattern completion per se...

journal_title：Neurobiology of learning and memory

authors： Kirwan CB,Gilbert PE,Kesner RP

更新日期：2005-01-01 00:00:00

abstract：:A common conceptualization of the organization of memory systems in brain is that different types of memory are mediated by distinct neural systems. Strong support for this view comes from studies that show double (or triple) dissociations between spatial, response, and emotional memories following selective lesions o...

journal_title：Neurobiology of learning and memory

authors： Mizumori SJ,Yeshenko O,Gill KM,Davis DM

更新日期：2004-11-01 00:00:00

abstract：:The prefrontal cortex is known to be involved in the acquisition of trace conditioning, a higher-cognitive form of Pavlovian conditioning in which a conditioned stimulus and an unconditioned stimulus are separated by a time gap. We have recently reported that medial prefrontal (mPFC) extracellular-signal regulated kin...

journal_title：Neurobiology of learning and memory

authors： Runyan JD,Dash PK

更新日期：2004-09-01 00:00:00

abstract：:Adult male Wistar rats with a substantia nigra pars compacta (SNc) lesion induced by intranigral administration of 1 micromol 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) were used as a model of early phase Parkinson's disease (PD). This lesion caused a partial depletion of striatal dopamine (DA). The animals w...

journal_title：Neurobiology of learning and memory

authors： Bellissimo MI,Kouzmine I,Ferro MM,de Oliveira BH,Canteras NS,Da Cunha C

更新日期：2004-09-01 00:00:00

abstract：:Several lines of evidence indicate that gamma-aminobutyric acid (GABA) type A (GABA(A)) receptors regulate memory consolidation. Here we studied the effect on consolidation of the selective antagonist of GABA(A) receptors, bicuculline, given into several regions of the cortex at different times after one-trial step-do...

journal_title：Neurobiology of learning and memory

authors： Luft T,Pereira GS,Cammarota M,Izquierdo I

更新日期：2004-07-01 00:00:00

abstract：:Glucocorticoid receptor activation within the basolateral amygdala (BLA) during fear conditioning may mediate enhancement in rats chronically exposed to stress levels of corticosterone. Male Sprague-Dawley rats received corticosterone (400 microg/ml) in their drinking water (days 1-21), a manipulation that was previou...

journal_title：Neurobiology of learning and memory

authors： Conrad CD,MacMillan DD 2nd,Tsekhanov S,Wright RL,Baran SE,Fuchs RA

更新日期：2004-05-01 00:00:00

abstract：:Activity dependent calcium entry into neurons can initiate a form of synaptic plasticity called long-term potentiation (LTP). This phenomenon is considered by many to be one possible cellular mechanism underlying learning and memory. The calcium entry that induces this phenomenon can occur when N-methyl-D-aspartate re...

journal_title：Neurobiology of learning and memory

authors： Woodside BL,Borroni AM,Hammonds MD,Teyler TJ

更新日期：2004-03-01 00:00:00

abstract：:There is extensive evidence that post-training administration of the adrenocortical hormone corticosterone facilitates memory consolidation processes in a variety of contextual and spatial-dependent learning situations. The present experiments examine whether corticosterone can modulate memory of auditory-cue classica...

journal_title：Neurobiology of learning and memory

authors： Hui GK,Figueroa IR,Poytress BS,Roozendaal B,McGaugh JL,Weinberger NM

更新日期：2004-01-01 00:00:00

abstract：:Acetylcholine plays an important role in regulating the processing of sensory stimuli, and understanding its specific cellular actions is critical to understanding how sensory cortex develops and functions in different behavioral states. Here we review recent work on the cellular effects of nicotinic receptor activati...

journal_title：Neurobiology of learning and memory

authors： Metherate R,Hsieh CY

更新日期：2003-11-01 00:00:00

abstract：:Nicotine has been demonstrated to enhance learning processes. The present experiments extend these results to examine the effects of nicotine on acquisition and consolidation of contextual and cued fear conditioning, and the duration of nicotine's enhancement of conditioned fear. C57BL/6 mice were trained with two pai...

journal_title：Neurobiology of learning and memory

authors： Gould TJ,Higgins JS

更新日期：2003-09-01 00:00:00

abstract：:Corticosterone (CORT), the predominant glucocorticoid in rodents, elevated for 21 days damages hippocampal subregion CA3. We tested the hypothesis that CORT would impair spatial memory, a hippocampal function. In each of the three experiments, rats received daily, subcutaneous injections of either CORT (26.8 mg/kg bod...

journal_title：Neurobiology of learning and memory

authors： Coburn-Litvak PS,Pothakos K,Tata DA,McCloskey DP,Anderson BJ

更新日期：2003-07-01 00:00:00

abstract：:Electrolytic lesions centered on the amygdaloid central nucleus (ACe) resulted in the inability of rats to acquire a Pavlovian conditional vocalization response. Conditioning consisted of pairing a light conditional stimulus with a tailshock unconditional stimulus (US). The thresholds of three unconditional responses ...

journal_title：Neurobiology of learning and memory

authors： Borszcz GS,Leaton RN

更新日期：2003-05-01 00:00:00

abstract：:Inhibitors of protein and mRNA syntheses inhibit long-term memory (LTM), but we lack information about the time windows during which those inhibitors are effective. Anisomycin (a protein synthesis translation inhibitor) was given to Hermissenda crassicornis which had received sufficient Pavlovian conditioning to produ...

journal_title：Neurobiology of learning and memory

authors： Epstein HT,Child FM,Kuzirian AM,Alkon DL

更新日期：2003-03-01 00:00:00

abstract：:Pre-test exposure to training-related cues is known to improve subsequent retention performance. To identify brain regions engaged in processes promoted by retrieval cues, a brain imaging approach using the [6-14C]glucose autoradiographic technique was used. Sprague-Dawley rats trained in a brightness discrimination a...

journal_title：Neurobiology of learning and memory

authors： Boujabit M,Bontempi B,Destrade C,Gisquet-Verrier P

更新日期：2003-01-01 00:00:00

abstract：:Induction of long-term synaptic changes at one synapse can facilitate the induction of long-term plasticity at another synapse. Here we show that if Aplysia sensory neuron (SN) somata and their remote motor neuron (MN) synapses are simultaneously exposed to serotonin (5HT) pulses, which at either site alone are insuff...

journal_title：Neurobiology of learning and memory

authors： Sherff CM,Carew TJ

更新日期：2002-11-01 00:00:00

abstract：:Drug addiction can be understood as a pathological subversion of normal brain learning and memory processes strengthened by the motivational impact of drug-associated stimuli, leading to the establishment of compulsive drug-seeking habits. Such habits evolve through a cascade of complex associative processes with Pavl...

journal_title：Neurobiology of learning and memory

authors： Robbins TW,Everitt BJ

更新日期：2002-11-01 00:00:00

abstract：:The single-trial passive avoidance task is a useful procedure for examining learning and memory in the young chick. However, it has recently been suggested that discrepant results reported by different laboratories are due to differences in training procedure. The present study investigated a number of parameters surr...

journal_title：Neurobiology of learning and memory

authors： Crowe SF,Hale MW

更新日期：2002-09-01 00:00:00

abstract：:Agmatine is a new putative neurotransmitter; however, the physiological role(s) of this endogenous released polyamine is still to be determined. We investigated its cognitive effect in an inhibitory avoidance task in adult rats. Agmatine (0.1, 1, 10, and 20 mg/kg) or saline was administered ip immediately after traini...

journal_title：Neurobiology of learning and memory

authors： Arteni NS,Lavinsky D,Rodrigues AL,Frison VB,Netto CA

更新日期：2002-09-01 00:00:00

abstract：:Intracerebral muscimol injection is widely used to inactivate discrete brain structures during behavioral tasks. However, little effort has been made to quantify the extent of muscimol diffusion. The authors report here electrophysiological and autoradiographic results obtained after muscimol injection (1 microg/micro...

journal_title：Neurobiology of learning and memory

authors： Edeline JM,Hars B,Hennevin E,Cotillon N

更新日期：2002-07-01 00:00:00

abstract：:Nitric oxide (NO) is a highly labile chemical messenger which has previously been implicated in memory processes in a variety of learning paradigms and species. However, there is only limited evidence to suggest which enzymes are acted upon by NO during the formation of memory. The present study investigates the role ...

journal_title：Neurobiology of learning and memory

authors： Edwards TM,Rickard NS,Ng KT

更新日期：2002-05-01 00:00:00

abstract：:This experiment tests the hypothesis that the cholinergic nucleus basalis magnocellularis (NBM) is necessary for complex or configural association learning, but not elemental or simple association learning. Male Long-Evans rats with bilateral 192 IgG-saporin lesions of the NBM (n = 12) and sham-operated controls (n = ...

journal_title：Neurobiology of learning and memory

authors： Butt AE,Bowman TD

更新日期：2002-03-01 00:00:00

abstract：:The authors evaluate a mapping of Rescorla and Wagner's (1972) behavioral model of classical conditioning onto the cerebellar substrates for motor reflex learning and illustrate how the limitations of the Rescorla-Wagner model are just as useful as its successes for guiding the development of new psychobiological theo...

journal_title：Neurobiology of learning and memory

authors： Gluck MA,Allen MT,Myers CE,Thompson RF

更新日期：2001-11-01 00:00:00

abstract：:Taste aversion learning is induced through two different behavioral procedures: a short-term or concurrent (two-daily flavors) and a long-term or sequential (one-daily flavor) procedure. For the concurrent group of animals, two gustatory/olfactory stimuli are presented separately but at the same time on a daily basis....

journal_title：Neurobiology of learning and memory

authors： Mediavilla C,Molina F,Puerto A

更新日期：2001-09-01 00:00:00

abstract：:The effect of calcium channel antagonists (CCA's) on working and reference memory in mice was studied using spontaneous alternation (SA) behavior in a T maze. Mice were given either one or four forced trials to either the right or the left arm on the training session (T1) followed by a free choice test (T2) at varying...

journal_title：Neurobiology of learning and memory

authors： Quartermain D,Garcia deSoria V

更新日期：2001-07-01 00:00:00

abstract：:The specific sigma-receptor agonist (+)-SKF 10047 and antagonist BD 1047 were used to investigate whether this receptor was involved in passive-avoidance training in the day-old chick. We found 300 microM (+)-SKF 10047 to be amnesic when injected into the lobus parolfactorius 5 h after training (p < .01). Higher or lo...

journal_title：Neurobiology of learning and memory

authors： Freeman FM,Young IG

更新日期：2001-05-01 00:00:00

abstract：:Goal-directed navigation is believed to be the combined product of idiothetic and allothetic orientation. Although both navigation systems require the hippocampal formation, it is probable that different circuits implement them. Examination of Long-Evans rats with dentate gyrus lesions induced by neonatal X-ray irradi...

journal_title：Neurobiology of learning and memory

authors： Czéh B,Stuchlik A,Wesierska M,Cimadevilla JM,Pokorný J,Seress L,Bures J

更新日期：2001-03-01 00:00:00

abstract：:The present study examined the effects of posttraining ethanol administration upon retention of an appetitive task using a variety of retention behaviors associated with the task. Male C57BL/6J mice were individually trained to find a cheese pellet placed in the corner of an open field. Five behavioral measures were u...

journal_title：Neurobiology of learning and memory

authors： Ladner CJ,Babbini M,Davies DL,Parker ES,Alkana RL

更新日期：2001-01-01 00:00:00

abstract：:Molecular genetic manipulation of the mouse offers the possibility of elucidating the function of individual gene products in neural systems underlying learning and memory. Many extant learning paradigms for mice rely on negative reinforcement, involve simple problems that are relatively rapidly acquired and thus prec...

journal_title：Neurobiology of learning and memory

authors： Brooks AI,Cory-Slechta DA,Murg SL,Federoff HJ

更新日期：2000-11-01 00:00:00

abstract：:Activation of N-methyl-d-aspartate (NMDA) receptors has been hypothesized to mediate certain forms of learning and memory. This hypothesis is based on the ability of competitive and uncompetitive NMDA receptor antagonists to disrupt learning. We investigated the effects of glycine site antagonists and partial agonists...

journal_title：Neurobiology of learning and memory

authors： Viu E,Zapata A,Capdevila J,Skolnick P,Trullas R

更新日期：2000-09-01 00:00:00

abstract：:In the marine snail Hermissenda, associative learning can be accomplished by paired presentations of light and vestibular stimulation. It is generally assumed that associative learning depends upon the intensity or salience of the conditioned or unconditioned stimulus (CS and US, respectively). Accordingly, during Her...

journal_title：Neurobiology of learning and memory

authors： Tomsic D,Alkon DL

更新日期：2000-07-01 00:00:00

abstract：:Mitogen-activated protein kinase (MAPK) is abundantly expressed in postmitotic neurons of the developed nervous system. MAPK is activated and required for induction of long-term potentiation (LTP) in the CA1 area of the hippocampus, which is blocked by the specific inhibitor of the MAPK kinase, PD 098059. Recently it ...

journal_title：Neurobiology of learning and memory

authors： Walz R,Roesler R,Quevedo J,Sant'Anna MK,Madruga M,Rodrigues C,Gottfried C,Medina JH,Izquierdo I

更新日期：2000-01-01 00:00:00